Characteristics of the circadian profile of heart rate during genetically determined hypertension

Abstract

Prevalence and importance of hypertension in the general incidence structure determines a wide range of research problems. Chronobiological indices are of great importance in the investigatory activity concerning mechanisms of essential hypertension. Our work was focused on the dynamics of HR circadian profile at different terms in male SHR rats with the use of telemetry monitoring. The obtained data showed considerable changes of cardiac rhythm in different time intervals which was understood as inhibition of the chronotropic function of the heart.

Keywords

• артериальное давление
• частота сердечных сокращений
• циркадианный индекс
• циркадианный профиль
• телеметрическое мониторирование
• крысы линии SHR