Asian Journal of Oncology (Jan 2017)

Colonic adenocarcinoma presenting as hemophagocytic syndrome

  • Murtaza Ali,
  • Siddharta Jain,
  • Naveet Wig,
  • Ashustosh Biswas,
  • Arvind Kumar,
  • Kuldeep Kumar

DOI
https://doi.org/10.4103/2454-6798.209332
Journal volume & issue
Vol. 03, no. 01
pp. 092 – 095

Abstract

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Hemophagocytic syndrome (hemophagocytic lymphohistiocytosis [HLH]) is a rare and potentially fatal disorder characterized by pathological immune activation associated with primary familial disorder, genetic mutation or occurring as a sporadic condition. The later can be secondary to infections, malignancies, or autoimmune diseases. Malignancy-associated HLH is commonly seen in hematological malignancies and rarely with solid organ tumors. We report a case of adenocarcinoma colon presenting as hemophagocytic syndrome. To the best of our knowledge, it is the first case report of HLH secondary to carcinoma colon.

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