Nature Communications (Mar 2020)
Environmental remodeling of human gut microbiota and antibiotic resistome in livestock farms
- Jian Sun,
- Xiao-Ping Liao,
- Alaric W. D’Souza,
- Manish Boolchandani,
- Sheng-Hui Li,
- Ke Cheng,
- José Luis Martínez,
- Liang Li,
- You-Jun Feng,
- Liang-Xing Fang,
- Ting Huang,
- Jing Xia,
- Yang Yu,
- Yu-Feng Zhou,
- Yong-Xue Sun,
- Xian-Bo Deng,
- Zhen-Ling Zeng,
- Hong-Xia Jiang,
- Bing-Hu Fang,
- You-Zhi Tang,
- Xin-Lei Lian,
- Rong-Min Zhang,
- Zhi-Wei Fang,
- Qiu-Long Yan,
- Gautam Dantas,
- Ya-Hong Liu
Affiliations
- Jian Sun
- National Risk Assessment Laboratory for Antimicrobial Resistance of Animal Original Bacteria, South China Agricultural University
- Xiao-Ping Liao
- National Risk Assessment Laboratory for Antimicrobial Resistance of Animal Original Bacteria, South China Agricultural University
- Alaric W. D’Souza
- The Edison Family Center for Genome Sciences and Systems Biology, Washington University in St. Louis School of Medicine
- Manish Boolchandani
- The Edison Family Center for Genome Sciences and Systems Biology, Washington University in St. Louis School of Medicine
- Sheng-Hui Li
- National Risk Assessment Laboratory for Antimicrobial Resistance of Animal Original Bacteria, South China Agricultural University
- Ke Cheng
- National Risk Assessment Laboratory for Antimicrobial Resistance of Animal Original Bacteria, South China Agricultural University
- José Luis Martínez
- Centro Nacional de Biotecnología, Consejo Superior de Investigaciones Científicas
- Liang Li
- National Risk Assessment Laboratory for Antimicrobial Resistance of Animal Original Bacteria, South China Agricultural University
- You-Jun Feng
- National Risk Assessment Laboratory for Antimicrobial Resistance of Animal Original Bacteria, South China Agricultural University
- Liang-Xing Fang
- National Risk Assessment Laboratory for Antimicrobial Resistance of Animal Original Bacteria, South China Agricultural University
- Ting Huang
- National Risk Assessment Laboratory for Antimicrobial Resistance of Animal Original Bacteria, South China Agricultural University
- Jing Xia
- National Risk Assessment Laboratory for Antimicrobial Resistance of Animal Original Bacteria, South China Agricultural University
- Yang Yu
- National Risk Assessment Laboratory for Antimicrobial Resistance of Animal Original Bacteria, South China Agricultural University
- Yu-Feng Zhou
- National Risk Assessment Laboratory for Antimicrobial Resistance of Animal Original Bacteria, South China Agricultural University
- Yong-Xue Sun
- National Risk Assessment Laboratory for Antimicrobial Resistance of Animal Original Bacteria, South China Agricultural University
- Xian-Bo Deng
- Guangdong Laboratory for Lingnan Modern Agriculture
- Zhen-Ling Zeng
- National Risk Assessment Laboratory for Antimicrobial Resistance of Animal Original Bacteria, South China Agricultural University
- Hong-Xia Jiang
- National Risk Assessment Laboratory for Antimicrobial Resistance of Animal Original Bacteria, South China Agricultural University
- Bing-Hu Fang
- National Risk Assessment Laboratory for Antimicrobial Resistance of Animal Original Bacteria, South China Agricultural University
- You-Zhi Tang
- National Risk Assessment Laboratory for Antimicrobial Resistance of Animal Original Bacteria, South China Agricultural University
- Xin-Lei Lian
- National Risk Assessment Laboratory for Antimicrobial Resistance of Animal Original Bacteria, South China Agricultural University
- Rong-Min Zhang
- National Risk Assessment Laboratory for Antimicrobial Resistance of Animal Original Bacteria, South China Agricultural University
- Zhi-Wei Fang
- Shenzhen Puensum Genetech Institute
- Qiu-Long Yan
- Shenzhen Puensum Genetech Institute
- Gautam Dantas
- The Edison Family Center for Genome Sciences and Systems Biology, Washington University in St. Louis School of Medicine
- Ya-Hong Liu
- National Risk Assessment Laboratory for Antimicrobial Resistance of Animal Original Bacteria, South China Agricultural University
- DOI
- https://doi.org/10.1038/s41467-020-15222-y
- Journal volume & issue
-
Vol. 11,
no. 1
pp. 1 – 11
Abstract
Environments where antibiotics are used indiscriminately exhibit microbial communities that can represent hot-spots of resistance gene enrichment, which in turn could spread to humans. Here, the authors characterize how exposure to swine farms environment lead to temporal changes in the gut microbiome and resistome of healthy veterinary students.
