Hormonal and Biochemical Characteristic of Patients with Ischemic Heart Disease and Adult Growth Hormone Deficiency

Abstract

In this article the authors analyzed the results of examination of 21 adult patients with ischemic heart disease against adult growth hormone deficiency. The decreasing of mean levels of growth hormone, LH in men and FSH in women in the first group of patients, and in the second group — decrease of mean levels of growth hormone, IGF-1, LH in men and FSH in women indicates the hypopituitarism in both groups of patients, as well as trend to the development of secondary hypogonadism in men. In patients of first and second groups we found increasing of the levels of total cholesterol, VLDL, atherogenic index (p < 0.05), more significant rise of mean levels of triglycerides (p < 0.01), at that more significant disorders of lipid and carbohydrate metabolism were detected in patients of second group. Average levels of LDL, HDL, conjugated bilirubin, urea, blood creatinine and fasting glycemia were also increased.

Keywords

• adult growth hormone deficiency
• ischemic heart disease
• obesity