Histopathological Effect of Some Gram Negative Bacteria on Intestinal Mucosa of Suckling Mice.

Abstract

The Histopathological Effect of Escherichia coli, Citrobacterfreundii and Klebseillaoxytoca on Intestinal Mucosa of mice were fed with 2*106cell/ml. The microscopic examination of the histological sections showed pathological changes in sucked mice with all bacterial type but depending on the bacterial type: Escherichia coli the more virulent and cause lymph inflteration with degeneration of vili and many polymorphonuclear leukocytes were seen in lamina propria. On the other hand, tissue damage of the mucosa with necrotic and entire sheets of epithelial cells had sloughed off in some parts. Klebseillaoxytoca the least virulent than Citrobacterfreundii and cause damage in the intestine cells when compared with the control organs.

Keywords

• suckling mice
• gram negative bacteria
• intestine