Advances in research on microRNAs regulating the development of myopia

De-Zheng Liu; Da-Dong Guo; Qian Li; Shan-Shan Wu; Xing-Rong Wang

doi:10.3980/j.issn.1672-5123.2020.2.18

Guoji Yanke Zazhi (Feb 2020)

Advances in research on microRNAs regulating the development of myopia

De-Zheng Liu,
Da-Dong Guo,
Qian Li,
Shan-Shan Wu,
Xing-Rong Wang

Affiliations

De-Zheng Liu: Shandong University of Traditional Chinese Medicine,Jinan 250014, Shandong Province, China; Shandong Provincial Key Laboratory of Integrated Traditional Chinese and Western Medicine for Prevention and Therapy of Ocular Diseases, Key Laboratory of Integrated Traditional Chinese and Western Medicine for Prevention an Therapy of Ocular Disease in University of Shandong, Eye Institute of Shandong University of Traditional Chinese Medicine, Jinan 250002, Shandong Province, China
Da-Dong Guo: Shandong Provincial Key Laboratory of Integrated Traditional Chinese and Western Medicine for Prevention and Therapy of Ocular Diseases, Key Laboratory of Integrated Traditional Chinese and Western Medicine for Prevention an Therapy of Ocular Disease in University of Shandong, Eye Institute of Shandong University of Traditional Chinese Medicine, Jinan 250002, Shandong Province, China
Qian Li: Shandong University of Traditional Chinese Medicine,Jinan 250014, Shandong Province, China; Shandong Provincial Key Laboratory of Integrated Traditional Chinese and Western Medicine for Prevention and Therapy of Ocular Diseases, Key Laboratory of Integrated Traditional Chinese and Western Medicine for Prevention an Therapy of Ocular Disease in University of Shandong, Eye Institute of Shandong University of Traditional Chinese Medicine, Jinan 250002, Shandong Province, China
Shan-Shan Wu: Shandong University of Traditional Chinese Medicine,Jinan 250014, Shandong Province, China; Shandong Provincial Key Laboratory of Integrated Traditional Chinese and Western Medicine for Prevention and Therapy of Ocular Diseases, Key Laboratory of Integrated Traditional Chinese and Western Medicine for Prevention an Therapy of Ocular Disease in University of Shandong, Eye Institute of Shandong University of Traditional Chinese Medicine, Jinan 250002, Shandong Province, China
Xing-Rong Wang: Affiliated Eye Hospital of Shandong University of Traditional Chinese Medicine, Jinan 250002, Shandong Province, China

DOI: https://doi.org/10.3980/j.issn.1672-5123.2020.2.18
Journal volume & issue: Vol. 20, no. 2
pp. 276 – 278

Abstract

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Myopia is one of the most common eye diseases in the world. MicroRNAs(miRNAs)are small, non-protein-coded single-stranded RNAs with a length of about 20-25 nucleotides,which are widely involved in the process of post-transcriptional regulation of many physiological and pathological processes of organisms. It has attracted extensive attention for the regulation role of miRNAs in the process of induction and development of myopia in recent years. This article reviews the regulatory role and related signal pathways of miRNAs in the development of myopia. It will provide highlights for the understanding of molecular mechanism of myopia and benefit for potential molecular diagnosis of myopia in the future.

Published in Guoji Yanke Zazhi

ISSN: 1672-5123 (Print)
Publisher: Press of International Journal of Ophthalmology (IJO PRESS)
Country of publisher: China
LCC subjects: Medicine: Ophthalmology
Website: http://ies.ijo.cn/

About the journal

Abstract

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