The Use of Neuromarker NSE, S100-B, GFAP Proteins in the Diagnosis and Treatment of Cerebral Ischemia in Patients with Aneurysmal Subarachnoid Hemorrhage

Abstract

The incidence of non-traumatic subarachnoid hemorrhage due to rupture of cerebral aneurysms and subsequent disability motivates the search for predictors of severe course and unfavorable outcome of the disease for early intensive treatment. NSE, S100-B, GFAP markers have proven themselves well for assessing the dynamics of treatment for diseases of the nervous system and detecting neurological nosologies. The use of the above proteins in aneurysmal hemorrhage opens up new perspectives in assessing the clinical status of the patient in the early stages, developing further treatment strategies, as well as helps draw conclusions about the outcome of the disease and possible disability of the patient. The studies collected in the review motivate continued research of the neuromarkers in aneurysmal hemorrhage.

Keywords

• subarachnoid hemorrhage
• neuromarkers of nontraumatic subarachnoid hemorrhage
• s100-b
• nse
• gfap
• prognostic factors of nontraumatic subarachnoid hemorrhage