Nature Communications (Nov 2018)

Invasive Salmonella exploits divergent immune evasion strategies in infected and bystander dendritic cell subsets

  • Anna Aulicino,
  • Kevin C. Rue-Albrecht,
  • Lorena Preciado-Llanes,
  • Giorgio Napolitani,
  • Neil Ashley,
  • Adam Cribbs,
  • Jana Koth,
  • B. Christoffer Lagerholm,
  • Tim Ambrose,
  • Melita A. Gordon,
  • David Sims,
  • Alison Simmons

DOI
https://doi.org/10.1038/s41467-018-07329-0
Journal volume & issue
Vol. 9, no. 1
pp. 1 – 17

Abstract

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Salmonella employ a range of strategies to counter host defences during infection. Here, Aulicino et al. use single-cell RNA-sequencing to examine the effects of invasive and non-invasive strains of Salmonella, revealing discrete and divergent immune evasion strategies in infected and bystander dendritic cells.