Nature Communications (Jun 2022)
Immunogenicity and reactogenicity of SARS-CoV-2 vaccines BNT162b2 and CoronaVac in healthy adolescents
- Jaime S. Rosa Duque,
- Xiwei Wang,
- Daniel Leung,
- Samuel M. S. Cheng,
- Carolyn A. Cohen,
- Xiaofeng Mu,
- Asmaa Hachim,
- Yanmei Zhang,
- Sau Man Chan,
- Sara Chaothai,
- Kelvin K. H. Kwan,
- Karl C. K. Chan,
- John K. C. Li,
- Leo L. H. Luk,
- Leo C. H. Tsang,
- Wilfred H. S. Wong,
- Cheuk Hei Cheang,
- Timothy K. Hung,
- Jennifer H. Y. Lam,
- Gilbert T. Chua,
- Winnie W. Y. Tso,
- Patrick Ip,
- Masashi Mori,
- Niloufar Kavian,
- Wing Hang Leung,
- Sophie Valkenburg,
- Malik Peiris,
- Wenwei Tu,
- Yu Lung Lau
Affiliations
- Jaime S. Rosa Duque
- Department of Paediatrics and Adolescent Medicine, The University of Hong Kong
- Xiwei Wang
- Department of Paediatrics and Adolescent Medicine, The University of Hong Kong
- Daniel Leung
- Department of Paediatrics and Adolescent Medicine, The University of Hong Kong
- Samuel M. S. Cheng
- School of Public Health, The University of Hong Kong
- Carolyn A. Cohen
- School of Public Health, The University of Hong Kong
- Xiaofeng Mu
- Department of Paediatrics and Adolescent Medicine, The University of Hong Kong
- Asmaa Hachim
- School of Public Health, The University of Hong Kong
- Yanmei Zhang
- Department of Paediatrics and Adolescent Medicine, The University of Hong Kong
- Sau Man Chan
- Department of Paediatrics and Adolescent Medicine, The University of Hong Kong
- Sara Chaothai
- School of Public Health, The University of Hong Kong
- Kelvin K. H. Kwan
- School of Public Health, The University of Hong Kong
- Karl C. K. Chan
- School of Public Health, The University of Hong Kong
- John K. C. Li
- School of Public Health, The University of Hong Kong
- Leo L. H. Luk
- School of Public Health, The University of Hong Kong
- Leo C. H. Tsang
- School of Public Health, The University of Hong Kong
- Wilfred H. S. Wong
- Department of Paediatrics and Adolescent Medicine, The University of Hong Kong
- Cheuk Hei Cheang
- Department of Paediatrics and Adolescent Medicine, The University of Hong Kong
- Timothy K. Hung
- Department of Paediatrics and Adolescent Medicine, The University of Hong Kong
- Jennifer H. Y. Lam
- Department of Paediatrics and Adolescent Medicine, The University of Hong Kong
- Gilbert T. Chua
- Department of Paediatrics and Adolescent Medicine, The University of Hong Kong
- Winnie W. Y. Tso
- Department of Paediatrics and Adolescent Medicine, The University of Hong Kong
- Patrick Ip
- Department of Paediatrics and Adolescent Medicine, The University of Hong Kong
- Masashi Mori
- Research Institute for Bioresources and Biotechnology, Ishikawa Prefectural University
- Niloufar Kavian
- School of Public Health, The University of Hong Kong
- Wing Hang Leung
- Department of Paediatrics and Adolescent Medicine, The University of Hong Kong
- Sophie Valkenburg
- School of Public Health, The University of Hong Kong
- Malik Peiris
- School of Public Health, The University of Hong Kong
- Wenwei Tu
- Department of Paediatrics and Adolescent Medicine, The University of Hong Kong
- Yu Lung Lau
- Department of Paediatrics and Adolescent Medicine, The University of Hong Kong
- DOI
- https://doi.org/10.1038/s41467-022-31485-z
- Journal volume & issue
-
Vol. 13,
no. 1
pp. 1 – 15
Abstract
There are adverse events associated with COVID-19 vaccines, such as myocarditis for adolescents following receipt of SARS-CoV-2 mRNA vaccines. Here the authors compare the immunogenicity and reactogenicity of two widely available SARS-CoV-2 vaccines (BNT162b2, an mRNA vaccine, and CoronaVac, a whole-virus inactivated vaccine) in healthy adolescents.
