High-frequency electrocautery and point-by-point ligation of anal warts combined with anal canal relaxation for treating condyloma acuminatum of the anal canal

Abstract

[Objectives] To investigate the clinical effect of high-frequency electrocautery and point-by-point ligation of anal warts combined with anal canal relaxation for treating condyloma acuminatum of the anal canal and its effect on anal morphology and function. [Methods] This was a retrospective analysis of 81 patients with condyloma acuminatum of the anal canal who were treated with high-frequency electrocautery and point-by-point ligation of anal warts combined with anal canal relaxation at the Department of Anorectal Diseases, Affiliated Hospital of Xuzhou Medical University, between January 2015 and April 2021. Clinical effectiveness was evaluated at 6, 12, and 24 weeks after surgery. Anal morphology and function (degree of anal stricture, degree of anal incontinence, and smoothness of defecation) were evaluated before and at 6, 12, and 24 weeks after surgery. [Results] All patients were considered cured after surgery with 100% resection of warts removal. The recurrence rate was 2.5%, 3.7%, and 9.8% at 6, 12, and 24 weeks after surgery. Patients with recurrence received immediate warts removal with high-frequency electric energy and recombinant human interferon α-2b topical gel; all patients with recurrence were considered cured 6 months after the last treatment. The degree of anal stricture did not differ significantly (P > 0.05) at different time points. The degree of anal incontinence after surgery (6, 12, and 24 weeks) was significantly lower than before surgery, and the degree of anal incontinence at 12 and 24 weeks was significantly lower than that at 6 weeks after surgery (P < 0.05). There were significant differences in the degree of smoothness of defecation at different time points (P < 0.05), and the degree of smoothness at 6, 12, and 24 weeks after surgery was significantly lower than before surgery (P < 0.05). [Conclusion] High-frequency electrocautery and point-by-point ligation of anal warts combined with anal canal relaxation have a certain advantage for treating condyloma acuminatum of the anal canal. It has satisfactory treatment effect while having little impact on anal morphology and function. It has the potential for wider clinical application.

Keywords

• condyloma acuminatum of the anal canal
• point-by-point ligation of anal warts
• anal canal relaxation