Use of natural medicine has been used by man since time immemorial, and this use has grown considerably in recent times. Thus, this study aims to make a comparator analysis regarding the phytochemical test, antioxidant activity and total phenolic content of the extracts of the leaves in ethanol and their respective fractions of Citrus limonium (lemon) and Capsicum frutescens L. (chilli pepper). To compare them was observed that ethanol extract of both plants showed the better antioxidant activity, Capsicum frutescens L. with 204.60 ppm and 99.07 ppm with Citrus limonium. With regard to the phenolic content of the hexane extract and lemon extract in ethanol pepper were those that showed a higher content. Overall, it was noted that Citrus limonium excelled both in relation to their antioxidant activity and the phenolic content.
