A nanotheranostic agent based on Nd3+-doped YVO4 with blood-brain-barrier permeability for NIR-II fluorescence imaging/magnetic resonance imaging and boosted sonodynamic therapy of orthotopic glioma

Affiliations

Zhijia Lv: State Key Laboratory of Rare Earth Resource Utilization, Changchun Institute of Applied Chemistry (CIAC), Chinese Academy of Sciences
Longhai Jin: Department of Radiology, The Second Hospital of Jilin University
Yue Cao: Department of Neurosurgery, The First Hospital of Jilin University
Hao Zhang: State Key Laboratory of Rare Earth Resource Utilization, Changchun Institute of Applied Chemistry (CIAC), Chinese Academy of Sciences
Dongzhi Xue: State Key Laboratory of Rare Earth Resource Utilization, Changchun Institute of Applied Chemistry (CIAC), Chinese Academy of Sciences
Na Yin: State Key Laboratory of Rare Earth Resource Utilization, Changchun Institute of Applied Chemistry (CIAC), Chinese Academy of Sciences
Tianqi Zhang: Department of Radiology, The Second Hospital of Jilin University
Yinghui Wang: State Key Laboratory of Rare Earth Resource Utilization, Changchun Institute of Applied Chemistry (CIAC), Chinese Academy of Sciences
Jianhua Liu: Department of Radiology, The Second Hospital of Jilin University
Xiaogang Liu: Department of Chemistry, National University of Singapore
Hongjie Zhang: State Key Laboratory of Rare Earth Resource Utilization, Changchun Institute of Applied Chemistry (CIAC), Chinese Academy of Sciences

Abstract

Nd3+-doped YVO4 nanotheranostic agent with blood-brain-barrier permeability could achieve NIR-II imaging/MRI and efficient SDT of orthotopic gliomas.

ISSN: 2047-7538 (Online)
Publisher: Nature Publishing Group
Country of publisher: United Kingdom
LCC subjects: Technology: Engineering (General). Civil engineering (General): Applied optics. Photonics; Science: Physics: Optics. Light
Website: https://www.nature.com/lsa/