Drug-induced liver injury in children – Case series from Mumbai

Abstract

Drug-induced liver injury is one of the most common and most important forms of injury to the liver, accounting for over 20%–40% of all instances of fulminant hepatic failure. We present five cases, of which four were started on antituberculosis therapy and one was started on a therapy for seizures with carbamazepine. All of them showed adverse reactions on the liver and its functioning as was evident by the raised liver enzymes or jaundice.

Keywords

• Anti-tuberculosis treatment
• drug-induced liver injury
• fulminant hepatic failure
• jaundice
• raised liver enzymes