Gut Bacterial Metabolites from Tryptophan and Phenylalanine Induce Melatonin Synthesis and Extend Sleep Duration in Mice

• Ji-Hyeok Lee,
• Su Jung Hwang,
• Song Lim Ham,
• Jonghwan Kim,
• Hye Jung Bang,
• Joon-Suk Park,
• Hyun-Hee Jang,
• Tae Yang Kim,
• Jeong Woo Park,
• Young Rok Seo,
• Byeong Soo Kim,
• Gon Sup Kim,
• Hyo-Jong Lee,
• Chung Sub Kim

Affiliations

Ji-Hyeok Lee

Department of Biohealth Regulatory Science, Sungkyunkwan University, Suwon, Republic of Korea

Su Jung Hwang

School of Pharmacy, Sungkyunkwan University, Suwon, Republic of Korea

Song Lim Ham

Department of Biopharmaceutical Convergence, Sungkyunkwan University, Suwon, Republic of Korea

Jonghwan Kim

Department of Biopharmaceutical Convergence, Sungkyunkwan University, Suwon, Republic of Korea

Hye Jung Bang

School of Pharmacy, Sungkyunkwan University, Suwon, Republic of Korea

Joon-Suk Park

Preclinical Research Center (PRC), Daegu-Gyeongbuk Medical Innovation Foundation (K-MEDI Hub), Daegu, Republic of Korea

Hyun-Hee Jang

Research Institute of Biological R&D Center, Eco-Prime Co., Changwon, Republic of Korea

Tae Yang Kim

Kick the Hurdle Co., Changwon, Republic of Korea

Jeong Woo Park

Kick the Hurdle Co., Changwon, Republic of Korea

Young Rok Seo

Kick the Hurdle Co., Changwon, Republic of Korea

Byeong Soo Kim

Kick the Hurdle Co., Changwon, Republic of Korea

Gon Sup Kim

Research Institute of Life Science and College of Veterinary Medicine, Gyeongsang National University, Jinju, Republic of Korea

Hyo-Jong Lee

School of Pharmacy, Sungkyunkwan University, Suwon, Republic of Korea

Chung Sub Kim

Department of Biohealth Regulatory Science, Sungkyunkwan University, Suwon, Republic of Korea