Nature Communications (Nov 2019)
Neonatal Wnt-dependent Lgr5 positive stem cells are essential for uterine gland development
Abstract
Uterine gland development is essential for successful embryo implantation, decidua formation and placental development. Here the authors demonstrate that neonatal Wnt-dependent Lgr5 expressing stem/progenitor cells at the tips of developing glands are indispensable for uterine gland development.