Case of Ibuprofen-Induced Liver Injury

Kirsten Wong; Beda Cha; Simon Wu

doi:10.7326/aimcc.2022.0880

Annals of Internal Medicine: Clinical Cases (Jan 2023)

Case of Ibuprofen-Induced Liver Injury

Kirsten Wong,
Beda Cha,
Simon Wu

Affiliations

Kirsten Wong: 1David Geffen School of Medicine, University of California, Los Angeles, California
Beda Cha: 1David Geffen School of Medicine, University of California, Los Angeles, California
Simon Wu: 1David Geffen School of Medicine, University of California, Los Angeles, California

DOI: https://doi.org/10.7326/aimcc.2022.0880
Journal volume & issue: Vol. 2, no. 1

Abstract

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Drug-induced liver injury (DILI) resulting from nonsteroidal anti-inflammatory drugs (NSAIDs) is a rare phenomenon; however, several cases have been reported in the literature and the LiverTox database. For ibuprofen in particular, only 22 cases have been reported, and the mechanism for liver injury is unclear. In this report, we discuss a case of ibuprofen-induced liver injury to highlight the evaluation of NSAID-induced DILI, as well as the likely mechanism of injury.

Published in Annals of Internal Medicine: Clinical Cases

ISSN: 2767-7664 (Online)
Publisher: American College of Physicians
Country of publisher: United States
LCC subjects: Medicine: Internal medicine
Website: https://www.acpjournals.org/journal/aimcc

About the journal