Data-driven analysis of a validated risk score for ovarian cancer identifies clinically distinct patterns during follow-up and treatment

Stefan Enroth; Emma Ivansson; Julia Hedlund Lindberg; Maria Lycke; Jessica Bergman; Anna Reneland; Karin Stålberg; Karin Sundfeldt; Ulf Gyllensten

doi:10.1038/s43856-022-00193-6

Communications Medicine (Oct 2022)

Data-driven analysis of a validated risk score for ovarian cancer identifies clinically distinct patterns during follow-up and treatment

Stefan Enroth,
Emma Ivansson,
Julia Hedlund Lindberg,
Maria Lycke,
Jessica Bergman,
Anna Reneland,
Karin Stålberg,
Karin Sundfeldt,
Ulf Gyllensten

Affiliations

Stefan Enroth: Department of Immunology, Genetics, and Pathology, Biomedical Center, SciLifeLab Uppsala, Uppsala University
Emma Ivansson: Department of Immunology, Genetics, and Pathology, Biomedical Center, SciLifeLab Uppsala, Uppsala University
Julia Hedlund Lindberg: Department of Immunology, Genetics, and Pathology, Biomedical Center, SciLifeLab Uppsala, Uppsala University
Maria Lycke: Department of Obstetrics and Gynecology, Institute of Clinical Sciences, Sahlgrenska Academy at Gothenburg University
Jessica Bergman: Olink Proteomics AB
Anna Reneland: Olink Proteomics AB
Karin Stålberg: Department of Women’s and Children’s Health, Uppsala University
Karin Sundfeldt: Department of Obstetrics and Gynecology, Institute of Clinical Sciences, Sahlgrenska Academy at Gothenburg University
Ulf Gyllensten: Department of Immunology, Genetics, and Pathology, Biomedical Center, SciLifeLab Uppsala, Uppsala University

DOI: https://doi.org/10.1038/s43856-022-00193-6
Journal volume & issue: Vol. 2, no. 1
pp. 1 – 13

Abstract

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Enroth et al. validate their previously developed 11-biomarker plasma protein-based risk-score for distinguishing benign vs. malignant ovarian tumors. The risk score is found to be informative of treatment outcome and predictive of 5-year survival.

Published in Communications Medicine

ISSN: 2730-664X (Online)
Publisher: Nature Portfolio
Country of publisher: United Kingdom
LCC subjects: Medicine
Website: https://www.nature.com/commsmed/

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