Journal of Integrative Bioinformatics (Mar 2023)

SBML level 3 package: spatial processes, version 1, release 1

  • Schaff James C.,
  • Lakshminarayana Anuradha,
  • Murphy Robert F.,
  • Bergmann Frank T.,
  • Funahashi Akira,
  • Sullivan Devin P.,
  • Smith Lucian P.

DOI
https://doi.org/10.1515/jib-2022-0054
Journal volume & issue
Vol. 20, no. 1

Abstract

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While many biological processes can be modeled by abstracting away the space in which those processes occur, some modeling (particularly at the cellular level) requires space itself to be modeled, with processes happening not in well-mixed compartments, but spatially-defined compartments. The SBML Level 3 Core specification does not include an explicit mechanism to encode geometries and spatial processes in a model, but it does provide a mechanism for SBML packages to extend the Core specification and add additional syntactic constructs. The SBML Spatial Processes package for SBML Level 3 adds the necessary features to allow models to encode geometries and other spatial information about the elements and processes it describes.