Ring Distortion of Vincamine Leads to the Identification of Re-Engineered Antiplasmodial Agents

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• Claribel Murillo-Solano,
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• Beau R. Brummel,
• David L. Perry,
• James R. Rocca,
• Debopam Chakrabarti,

Affiliations

Department of Medicinal Chemistry, Center for Natural Products, Drug Discovery and Development (CNPD3), University of Florida, Gainesville, Florida, United States

Claribel Murillo-Solano

Division of Molecular Microbiology, Burnett School of Biomedical Sciences, University of Central Florida, Orlando, Florida, United States

Department of Medicinal Chemistry, Center for Natural Products, Drug Discovery and Development (CNPD3), University of Florida, Gainesville, Florida, United States

Beau R. Brummel

Department of Medicinal Chemistry, Center for Natural Products, Drug Discovery and Development (CNPD3), University of Florida, Gainesville, Florida, United States

David L. Perry

Division of Molecular Microbiology, Burnett School of Biomedical Sciences, University of Central Florida, Orlando, Florida, United States

James R. Rocca

Department of Medicinal Chemistry, Center for Natural Products, Drug Discovery and Development (CNPD3), University of Florida, Gainesville, Florida, United States

Debopam Chakrabarti

Division of Molecular Microbiology, Burnett School of Biomedical Sciences, University of Central Florida, Orlando, Florida, United States

Department of Medicinal Chemistry, Center for Natural Products, Drug Discovery and Development (CNPD3), University of Florida, Gainesville, Florida, United States