Left ventricular function in patients with cardiorenal pathology and chronic renal failure

Abstract

Prognosis inpatients with pre-dialysis stages of chronic renal failure (CRF) is determined by various factors, including left ventricular hypertrophy (LVH) and coronary heart disease (CHD). At the same time, remodeling features and diastolic LV myocardial function in CRF patients are still understudied. The present study aimed to assess structural and functional LV features inpatients with early CRF stages and combined cardio-renal pathology. Among 70 patients with CHF and secondary arterial hypertension (AH), 35 also had CHD. According to clinical and echocardiography data, patients with combined cardio-renal pathology often had concentric and eccentric LVH types, as well as hypertrophic and pseudo-normal variants of LV diastolic dysfunction. Ln patients with CRF and symptomatic AH, eccentric LVH type or pseudo-normal diastolic dysfunction variant were not diagnosed. Chronic heart failure (CHF) symptoms in patients with CRF, secondary AH and CHD, were of systolo-diastolic nature; CHD-free participants had diastolic CHF.

Keywords

• chronic renal failure
• cardio
• renal pathology
• remodeling features diastolic
• diastolic lv myocardial function