Can CSF spectrophotometry for “Xanthochromia” be used to detect leaking subarachnoid aneurysms in patients with sickle cell anemia with negative MRI or CT angiogram despite hyperbilirubinemia?

Abstract

Abstract CSF (Cerebrospinal Fluid) xanthochromia by spectroscopy should not be dismissed in the context of hyperbilirubinemia in a patient with sickle cell anemia. Xanthochromia detected by spectrophotometry offers a vital clue that further invasive diagnosis is required.

Keywords

• CSF xanthochromia
• polycystic kidney disease
• Sickle cell anemia
• spectroscopy
• subarachnoid hemorrhage