ACS Central Science (Nov 2020)
Chemogenetic System Demonstrates That Cas9 Longevity Impacts Genome Editing Outcomes
- Vedagopuram Sreekanth,
- Qingxuan Zhou,
- Praveen Kokkonda,
- Heysol C. Bermudez-Cabrera,
- Donghyun Lim,
- Benjamin K. Law,
- Benjamin R. Holmes,
- Santosh K. Chaudhary,
- Rajaiah Pergu,
- Brittany S. Leger,
- James A. Walker,
- David K. Gifford,
- Richard I. Sherwood,
- Amit Choudhary
Affiliations
- Vedagopuram Sreekanth
- Chemical Biology and Therapeutics Science Program, Broad Institute of MIT and Harvard, Cambridge, Massachusetts, United States
- Qingxuan Zhou
- Chemical Biology and Therapeutics Science Program, Broad Institute of MIT and Harvard, Cambridge, Massachusetts, United States
- Praveen Kokkonda
- Chemical Biology and Therapeutics Science Program, Broad Institute of MIT and Harvard, Cambridge, Massachusetts, United States
- Heysol C. Bermudez-Cabrera
- Department of Medicine, Harvard Medical School, Boston, Massachusetts, United States
- Donghyun Lim
- Chemical Biology and Therapeutics Science Program, Broad Institute of MIT and Harvard, Cambridge, Massachusetts, United States
- Benjamin K. Law
- Chemical Biology and Therapeutics Science Program, Broad Institute of MIT and Harvard, Cambridge, Massachusetts, United States
- Benjamin R. Holmes
- McGovern Institute for Brain Research at MIT, Cambridge, Massachusetts, United States
- Santosh K. Chaudhary
- Chemical Biology and Therapeutics Science Program, Broad Institute of MIT and Harvard, Cambridge, Massachusetts, United States
- Rajaiah Pergu
- Chemical Biology and Therapeutics Science Program, Broad Institute of MIT and Harvard, Cambridge, Massachusetts, United States
- Brittany S. Leger
- Center for Genomic Medicine, Massachusetts General Hospital, Boston, Massachusetts, United States
- James A. Walker
- Center for Genomic Medicine, Massachusetts General Hospital, Boston, Massachusetts, United States
- David K. Gifford
- McGovern Institute for Brain Research at MIT, Cambridge, Massachusetts, United States
- Richard I. Sherwood
- Department of Medicine, Harvard Medical School, Boston, Massachusetts, United States
- Amit Choudhary
- Chemical Biology and Therapeutics Science Program, Broad Institute of MIT and Harvard, Cambridge, Massachusetts, United States
- DOI
- https://doi.org/10.1021/acscentsci.0c00129
- Journal volume & issue
-
Vol. 6,
no. 12
pp. 2228 – 2237
Abstract
No abstracts available.