Molecules (Sep 2019)

Recent Advances on Iron(III) Selective Fluorescent Probes with Possible Applications in Bioimaging

  • Suban K. Sahoo,
  • Guido Crisponi

DOI
https://doi.org/10.3390/molecules24183267
Journal volume & issue
Vol. 24, no. 18
p. 3267

Abstract

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Iron(III) is well-known to play a vital role in a variety of metabolic processes in almost all living systems, including the human body. However, the excess or deficiency of Fe3+ from the normal permissible limit can cause serious health problems. Therefore, novel analytical methods are developed for the simple, direct, and cost-effective monitoring of Fe3+ concentration in various environmental and biological samples. Because of the high selectivity and sensitivity, fast response time, and simplicity, the fluorescent-based molecular probes have been developed extensively in the past few decades to detect Fe3+. This review was narrated to summarize the Fe3+-selective fluorescent probes that show fluorescence enhancement (turn-on) and ratiometric response. The Fe3+ sensing ability, mechanisms along with the analytical novelties of recently reported 77 fluorescent probes are discussed.

Keywords