Quantitative Prediction of Drug–Drug Interactions Involving Inhibitory Metabolites by Physiologically Based Pharmacokinetic Models: Is it Worth It?

• M Tod,
• S Goutelle,
• L Bourguignon,
• N Bleyzac

Affiliations

M Tod

Groupement Hospitalier Nord, Hospices Civils de LyonLyon France

S Goutelle

Groupement Hospitalier Nord, Hospices Civils de LyonLyon France

L Bourguignon

Groupement Hospitalier Nord, Hospices Civils de LyonLyon France

N Bleyzac

EMR3738, Université Claude Bernard Lyon 1Lyon France