Nature Communications (Dec 2022)

Effectiveness of ChAdOx1-S COVID-19 booster vaccination against the Omicron and Delta variants in England

  • Freja Cordelia Møller Kirsebom,
  • Nick Andrews,
  • Ruchira Sachdeva,
  • Julia Stowe,
  • Mary Ramsay,
  • Jamie Lopez Bernal

DOI
https://doi.org/10.1038/s41467-022-35168-7
Journal volume & issue
Vol. 13, no. 1
pp. 1 – 9

Abstract

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Vaccine effectiveness of a ChAdOx1-S booster was estimated in a test-negative case-control study in England. Protection was found to be moderate against mild disease but remained high and comparable to that of an mRNA booster against hospitalisation with Omicron.