A heterophil/lymphocyte-selected population reveals the phosphatase PTPRJ is associated with immune defense in chickens

Jie Wang; Jin Zhang; Qiao Wang; Qi Zhang; Mamadou Thiam; Bo Zhu; Fan Ying; Mohamed Shafey Elsharkawy; Maiqing Zheng; Jie Wen; Qinghe Li; Guiping Zhao

doi:10.1038/s42003-023-04559-x

Communications Biology (Feb 2023)

A heterophil/lymphocyte-selected population reveals the phosphatase PTPRJ is associated with immune defense in chickens

Jie Wang,
Jin Zhang,
Qiao Wang,
Qi Zhang,
Mamadou Thiam,
Bo Zhu,
Fan Ying,
Mohamed Shafey Elsharkawy,
Maiqing Zheng,
Jie Wen,
Qinghe Li,
Guiping Zhao

Affiliations

Jie Wang: Institute of Animal Sciences, Chinese Academy of Agricultural Sciences, State Key Laboratory of Animal Nutrition
Jin Zhang: Institute of Animal Sciences, Chinese Academy of Agricultural Sciences, State Key Laboratory of Animal Nutrition
Qiao Wang: Institute of Animal Sciences, Chinese Academy of Agricultural Sciences, State Key Laboratory of Animal Nutrition
Qi Zhang: Institute of Animal Sciences, Chinese Academy of Agricultural Sciences, State Key Laboratory of Animal Nutrition
Mamadou Thiam: Institute of Animal Sciences, Chinese Academy of Agricultural Sciences, State Key Laboratory of Animal Nutrition
Bo Zhu: Institute of Animal Sciences, Chinese Academy of Agricultural Sciences, State Key Laboratory of Animal Nutrition
Fan Ying: Institute of Animal Sciences, Chinese Academy of Agricultural Sciences, State Key Laboratory of Animal Nutrition
Mohamed Shafey Elsharkawy: Institute of Animal Sciences, Chinese Academy of Agricultural Sciences, State Key Laboratory of Animal Nutrition
Maiqing Zheng: Institute of Animal Sciences, Chinese Academy of Agricultural Sciences, State Key Laboratory of Animal Nutrition
Jie Wen: Institute of Animal Sciences, Chinese Academy of Agricultural Sciences, State Key Laboratory of Animal Nutrition
Qinghe Li: Institute of Animal Sciences, Chinese Academy of Agricultural Sciences, State Key Laboratory of Animal Nutrition
Guiping Zhao: Institute of Animal Sciences, Chinese Academy of Agricultural Sciences, State Key Laboratory of Animal Nutrition

DOI: https://doi.org/10.1038/s42003-023-04559-x
Journal volume & issue: Vol. 6, no. 1
pp. 1 – 12

Abstract

Read online

Genomic and transcriptomic profiling in Jingxing yellow chickens selected for a heterophil-lymphocyte ratio (H/L) provides further insight on the genetic basis of H/L and identifies PTPRJ as a relevant factor.

Published in Communications Biology

ISSN: 2399-3642 (Online)
Publisher: Nature Portfolio
Country of publisher: United Kingdom
LCC subjects: Science: Biology (General)
Website: https://www.nature.com/commsbio/

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