ABCD: Arquivos Brasileiros de Cirurgia Digestiva (Jun 2018)

SALIVARY CORTISOL AND METABOLIC SYNDROME COMPONENT’S ASSOCIATION

  • Grasiane Izidorio GARBELLOTTO,
  • Fernanda Jardim REIS,
  • Ana Maria Pandolfo FEOLI,
  • Carla Haas PIOVESAN,
  • Andréia da Silva GUSTAVO,
  • Margareth da Silva OLIVEIRA,
  • Fabrício Edler MACAGNAN,
  • Carlos Alexandre Sanchez FERREIRA,
  • Moisés Evandro BAUER,
  • Cácio Ricardo WIETZYCOSKI

DOI
https://doi.org/10.1590/0102-672020180001e1351
Journal volume & issue
Vol. 31, no. 1

Abstract

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ABSTRACT Background: Actually the lifestyle exposes the population to several risk factors related to alimentary habits and less physical activity that contributes to chronic diseases appearance worldwide. Aim: To analyze the association between salivary cortisol and the components of metabolic syndrome. Methods: This is a cross-sectional study. As part of it, 28 individuals aged 30-59 years presenting three or more of the following findings: CA: ≥88 cm for women and ≥102 cm for men; SBP>130 mmHg and DBP>85 mmHg; GL>100 mg/dl; TG>150 mg/dl; HDL110mg/dl, have significantly lower average levels of cortisol than ones with FPG <110 (12.8±5,2 vs. 17.3±4.2). Significant correlations were HOMA vs. WC (r=0,465; p˂0,005) and TG (r=0,473; p˂0,005), WC vs. FG (r=0,446; p˂0,005) and BMI (r=0,730; p˂0.0001); TG vs. HDL (r=0,441 p˂0,005) and FG (r=0,440; p˂0,005). Conclusion: Morning salivary cortisol in subjects with chronically elevated blood glucose can represent a downregulation of the hypothalamic-pituitary adrenal axis. This is an important finding not yet well investigated.

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