DIAGNOSIS OF HYPOXIC-ISCHEMIC CENTRAL NERVOUS SYSTEM INJURIES IN A NEWBORN BABY

Abstract

Purpose: to determine the diagnostic value of Doppler velocimetry with reference to neurospecific compounds during the early neonatal period depending on the delivery management.Materials and methods: 65 pregnant women and newborns were examined. They were retrospectively divided into three clinical groups formed according to neonatologists`s final diagnosis in newborns. Before delivery pregnant women had Doppler velocimetry.Results: by progressing hypoxemia there is a dilation of the medial cerebral artery of the fetus resulting in the increase of oxygenation of brain tissue of the fetus and in the increase of specific markers of neurologic disturbances.Conclusion: determination of neurospecific proteins in umbilical blood in newborns is an early method of detection of the central nervous system injury permitting to diagnose pathological conditions and prognosticate a delayed manifestation of brain damages on time without reference to the delivery method.

Keywords

• hypoxia
• neurospecific proteins
• vasoactive peptides
• doppler velocimetry