Nature Communications (Oct 2018)

Direct electrical quantification of glucose and asparagine from bodily fluids using nanopores

  • Nicole Stéphanie Galenkamp,
  • Misha Soskine,
  • Jos Hermans,
  • Carsten Wloka,
  • Giovanni Maglia

DOI
https://doi.org/10.1038/s41467-018-06534-1
Journal volume & issue
Vol. 9, no. 1
pp. 1 – 8

Abstract

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Protein nanopores are emerging as sensors for a variety of biomolecules. Here the authors develop a nanopore based on the bacterial toxin ClyA, in conjunction with binding proteins for glucose and asparagine, to detect these biomolecules simultaneously from a variety of unprocessed, diluted body fluids.