1444 Pharmacologic LDH inhibition redirects intratumoral glucose consumption and improves response to CTLA-4 blockade

• Jedd D Wolchok,
• Taha Merghoub,
• Sadna Budhu,
• Roberta Zappasodi,
• Svena Verma,
• Inna Serganova,
• Lauren Dong,
• Levi Mark Mangarin,
• Yacine Marouf,
• Jonathan F Khan

Affiliations

Jedd D Wolchok

1Weill Cornell Medicine, New York, NY, USA

Taha Merghoub

1Weill Cornell Medicine, New York, NY, USA

Sadna Budhu

1Weill Cornell Medicine, New York, NY, USA

Roberta Zappasodi

1Weill Cornell Medicine, New York, NY, USA

Svena Verma

1Weill Cornell Medicine, New York, NY, USA

Inna Serganova

1Weill Cornell Medicine, New York, NY, USA

Lauren Dong

2Memorial Sloan Kettering Cancer Center, New York, NY, USA

Levi Mark Mangarin

1Weill Cornell Medicine, New York, NY, USA

Yacine Marouf

1Weill Cornell Medicine, New York, NY, USA

Jonathan F Khan

2Memorial Sloan Kettering Cancer Center, Floral Park, NY, USA