Expediency of radiation therapy and adjuvant polychemotherapy in surgical treatment of cancer

Abstract

The analysis of the effectiveness of different methods of treatment of patients with gastric cancer have been conducted. In additional to surgery methods of antitumor action – preoperative radiation therapy (combination therapy), adjuvant chemotherapy allowed to improve survival in patients with locally advanced gastric cancer as compared with surgical method only. On the early stages of gastric cancer surgery may be the only and final treatment. Indicators of long-term survival in usage of routine treatment options (surgery and irradiation) or adjuvant chemotherapy improved by 1.5-2 times, and were the highest in the group with combined radiotherapy (5-year survival rate - 25%). Improvement of resection procedures in gastric cancer in combination with appearing of targeted, immunomodulatory drugs, increasing possibility of high-precision equipment improve long-term results as well. Thus, improvement of treatment methods of gastric cancer requires search for and application of new advanced modes of systemic and combined treatment.

Keywords

• gastric cancer
• surgical treatment
• combined method
• adjuvant chemotherapy
• remote survival