Chinese Medical Journal (Jan 2015)

High Killips Class as a Predictor of New-onset Atrial Fibrillation Following Acute Myocardial Infarction: Systematic Review and Meta-analysis

  • En-Yuan Zhang,
  • Li Cui,
  • Zhen-Yu Li,
  • Tong Liu,
  • Guang-Ping Li

DOI
https://doi.org/10.4103/0366-6999.160565
Journal volume & issue
Vol. 128, no. 14
pp. 1964 – 1968

Abstract

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Background: Recent observational studies have shown that patients with higher Killips score (>I) have higher risk of new-onset atrial fibrillation (NOAF) following acute myocardial infarction (AMI), while others drew a neutral conclusion. The ultimate predictive value of high Killips class on NOAF remained obscure. Methods: PubMed, Web of Science, China National Knowledge Infrastructure, and the Cochrane Controlled Trials Register Databases were searched until February 2015. Of the 3732 initially identified studies, 5 observational studies with 10,053 patients were analyzed. Results: The meta-analysis of these studies showed that higher Killips score on admission was associated with higher incidence of NOAF following AMI (odds ratio = 2.29, 95% confidence interval 1.96-2.67, P I was associated with the higher opportunity of developing NOAF following AMI.

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