Trehalose Recycling Promotes Energy-Efficient Biosynthesis of the Mycobacterial Cell Envelope

Amol Arunrao Pohane; Caleb R. Carr; Jaishree Garhyan; Benjamin M. Swarts; M. Sloan Siegrist

doi:10.1128/mBio.02801-20

mBio (Feb 2021)

Trehalose Recycling Promotes Energy-Efficient Biosynthesis of the Mycobacterial Cell Envelope

Amol Arunrao Pohane,
Caleb R. Carr,
Jaishree Garhyan,
Benjamin M. Swarts,
M. Sloan Siegrist

Affiliations

Amol Arunrao Pohane: Department of Microbiology, University of Massachusetts, Amherst, Massachusetts, USA
Caleb R. Carr: Department of Microbiology, University of Massachusetts, Amherst, Massachusetts, USA
Jaishree Garhyan: Department of Microbiology, University of Massachusetts, Amherst, Massachusetts, USA
Benjamin M. Swarts: Department of Chemistry and Biochemistry, Central Michigan University, Mount Pleasant, Michigan, USA
M. Sloan Siegrist: ORCiD; Department of Microbiology, University of Massachusetts, Amherst, Massachusetts, USA

DOI: https://doi.org/10.1128/mBio.02801-20
Journal volume & issue: Vol. 12, no. 1

Abstract

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The mycomembrane layer of the mycobacterial cell envelope is a barrier to environmental, immune, and antibiotic insults. There is considerable evidence of mycomembrane plasticity during infection and in response to host-mimicking stresses.

Published in mBio

ISSN: 2161-2129 (Print); 2150-7511 (Online)
Publisher: American Society for Microbiology
Country of publisher: United States
LCC subjects: Science: Microbiology
Website: https://journals.asm.org/journal/mbio

About the journal