Urovni rezistina, adiponektinai insulinorezistentnosti u patsientov s raznoystepen'yu narusheniy uglevodnogo obmena

Abstract

The basis of type 2 diabetes is obesity and insulin resistance. Fat tissue is hormonaly active system which produces adiponectin, resistin and other adipokines. These substances participate in development of insulin resistance. The article presents the results of a study conducted to examine the role of adiponectin, resistin in development of insulin resistance in patients with IGT and type 2 diabetes. The reduction of adiponectin level and insulin resistance was found in women suffering from IGF or type 2 diabetes and in men with only type 2 diabetes. Resistin levels were increased in the examined patients with IGT and with type 2 diabetes.

Keywords

• diabetes mellitus type 2
• impaired glucose tolerance
• insulin resistance
• insulin
• adiponectin
• resistin