P1408: MONOALLELIC AND BIALLELIC GERMLINE MUTATIONS AFFECTING THE TRANSCRIPTION FACTOR HELIOS CAUSE PLEIOTROPIC DEFECTS OF IMMUNITY

• D. Mayr,
• T. Shahin,
• M. Shoeb,
• H. S. Kuehn,
• B. Hoeger,
• S. Giuliani,
• L. Gawriyski,
• Ö. Yüce Petronczki,
• J. Hadjadj,
• S. Köstel Bal,
• S. Zoghi,
• M. Haimel,
• R. Jimenez Heredia,
• D. Boutboul,
• M. Triebwasser,
• F. Rialland-Battisti,
• S. Tangye,
• T. Fleisher,
• N. Rezaei,
• N. Romberg,
• S. Latour,
• M. Varjosalo,
• F. Halbritter,
• F. Rieux-Laucat,
• I. Castanon,
• S. Rosenzweig,
• K. Boztug

Affiliations

D. Mayr

1 St. Anna Children’s Cancer Research Institute, Vienna, Austria

T. Shahin

1 St. Anna Children’s Cancer Research Institute, Vienna, Austria

M. Shoeb

1 St. Anna Children’s Cancer Research Institute, Vienna, Austria

H. S. Kuehn

2 Immunology Service, Department of Laboratory Medicine, National Institutes of Health, Bethesda, United States of America

B. Hoeger

1 St. Anna Children’s Cancer Research Institute, Vienna, Austria

S. Giuliani

1 St. Anna Children’s Cancer Research Institute, Vienna, Austria

L. Gawriyski

3 Institute of Biotechnology, Helsinki Institute of Life Science, Proteomics Unit, University of Helsinki, Helsinki, Finland

Ö. Yüce Petronczki

1 St. Anna Children’s Cancer Research Institute, Vienna, Austria

J. Hadjadj

4 Laboratory of Immunogenetics of Pediatric Autoimmune Diseases, Institut Imagine, INSERM Unité Mixte de Recherche (UMR) 1163

S. Köstel Bal

1 St. Anna Children’s Cancer Research Institute, Vienna, Austria

S. Zoghi

1 St. Anna Children’s Cancer Research Institute, Vienna, Austria

M. Haimel

1 St. Anna Children’s Cancer Research Institute, Vienna, Austria

R. Jimenez Heredia

1 St. Anna Children’s Cancer Research Institute, Vienna, Austria

D. Boutboul

5 Laboratory of Lymphocyte Activation and Susceptibility to EBV Infection, INSERM UMR 1163, Paris, France

M. Triebwasser

6 Division of Immunology and Allergy, The Children’s Hospital of Philadelphia and Department of Pediatrics, The Perelman School of Medicine at the University of Pennsylvania, Philadelphia, United States of America

F. Rialland-Battisti

7 Pediatric onco-hematology department, CHU de Nantes, Nantes, France

S. Tangye

8 Garvan Institute of Medical Research, Darlinghurst, Australia

T. Fleisher

2 Immunology Service, Department of Laboratory Medicine, National Institutes of Health, Bethesda, United States of America

N. Rezaei

9 Research Center for Immunodeficiencies, Children’s Medical Center, Tehran, Iran

N. Romberg

6 Division of Immunology and Allergy, The Children’s Hospital of Philadelphia and Department of Pediatrics, The Perelman School of Medicine at the University of Pennsylvania, Philadelphia, United States of America

S. Latour

5 Laboratory of Lymphocyte Activation and Susceptibility to EBV Infection, INSERM UMR 1163, Paris, France

M. Varjosalo

3 Institute of Biotechnology, Helsinki Institute of Life Science, Proteomics Unit, University of Helsinki, Helsinki, Finland

F. Halbritter

1 St. Anna Children’s Cancer Research Institute, Vienna, Austria

F. Rieux-Laucat

4 Laboratory of Immunogenetics of Pediatric Autoimmune Diseases, Institut Imagine, INSERM Unité Mixte de Recherche (UMR) 1163

I. Castanon

1 St. Anna Children’s Cancer Research Institute, Vienna, Austria

S. Rosenzweig

2 Immunology Service, Department of Laboratory Medicine, National Institutes of Health, Bethesda, United States of America

K. Boztug

1 St. Anna Children’s Cancer Research Institute, Vienna, Austria