Molecular Mechanisms in Lysosomal Storage Diseases: From Pathogenesis to Therapeutic Strategies

Valeria De Pasquale; Melania Scarcella; Luigi Michele Pavone

doi:10.3390/biomedicines10040922

Biomedicines (Apr 2022)

Molecular Mechanisms in Lysosomal Storage Diseases: From Pathogenesis to Therapeutic Strategies

Valeria De Pasquale,
Melania Scarcella,
Luigi Michele Pavone

Affiliations

Valeria De Pasquale: Department of Veterinary Medicine and Animal Productions, University of Naples Federico II, Via F. Delpino 1, 80127 Naples, Italy
Melania Scarcella: Department of Molecular Medicine and Medical Biotechnology, University of Naples Federico II, Via S. Pansini 5, 80131 Naples, Italy
Luigi Michele Pavone: Department of Molecular Medicine and Medical Biotechnology, University of Naples Federico II, Via S. Pansini 5, 80131 Naples, Italy

DOI: https://doi.org/10.3390/biomedicines10040922
Journal volume & issue: Vol. 10, no. 4
p. 922

Abstract

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Lysosomal storage diseases (LSDs) are a group of metabolic diseases caused by inborn mutations of lysosomal enzymes, which lead to lysosome substrate accumulation in various cell types [...]

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Published in Biomedicines

ISSN: 2227-9059 (Online)
Publisher: MDPI AG
Country of publisher: Switzerland
LCC subjects: Science: Biology (General)
Website: http://www.mdpi.com/journal/biomedicines

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Abstract

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