Open Medicine
(Jul 2024)
Population pharmacokinetics of meropenem in critically ill patients
Rančić Aleksandar,
Milosavljević Miloš N.,
Rosić Nikola,
Milovanović Dragan,
Folić Marko,
Zečević Dejana Ružić,
Petrović Nemanja,
Čorbić Mirjana Milojević,
Dabanović Vera,
Janković Slobodan M.
Affiliations
Rančić Aleksandar
Institute of Public Health Kragujevac, Kragujevac, Serbia
Milosavljević Miloš N.
Department of Pharmacology and Toxicology, Faculty of Medical Sciences, University of Kragujevac, Svetozara Markovica 69, Kragujevac, 34000, Serbia
Rosić Nikola
Clinical Pharmacology Department, University Clinical Centre Kragujevac, Kragujevac, Serbia
Milovanović Dragan
Department of Pharmacology and Toxicology, Faculty of Medical Sciences, University of Kragujevac, Svetozara Markovica 69, Kragujevac, 34000, Serbia
Folić Marko
Department of Pharmacy, Faculty of Medical Sciences, University of Kragujevac, Kragujevac, 34000, Serbia
Zečević Dejana Ružić
Department of Pharmacology and Toxicology, Faculty of Medical Sciences, University of Kragujevac, Svetozara Markovica 69, Kragujevac, 34000, Serbia
Petrović Nemanja
Department of Pharmacology and Toxicology, Faculty of Medical Sciences, University of Kragujevac, Svetozara Markovica 69, Kragujevac, 34000, Serbia
Čorbić Mirjana Milojević
Clinical Pharmacology Department, University Clinical Centre Kragujevac, Kragujevac, Serbia
Dabanović Vera
Pharmacy Institution of Montenegro “Montefarm”, Podgorica, Montenegro
Janković Slobodan M.
Department of Pharmacology and Toxicology, Faculty of Medical Sciences, University of Kragujevac, Svetozara Markovica 69, Kragujevac, 34000, Serbia
DOI
https://doi.org/10.1515/med-2024-1004
Journal volume & issue
Vol. 19,
no. 1
Abstract
Read online
The pharmacokinetics of meropenem are significantly altered in critically ill patients. A population pharmacokinetic study was designed to estimate typical values of meropenem clearance in critically ill patients and evaluate potential factors of influence.
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