Update of pathology in medullary thyroid carcinoma

LIU Zhiyan, YU Yaling, KAKUDO Kennichi

doi:10.16139/j.1007-9610.2023.06.03

Waike lilun yu shijian (Nov 2023)

Update of pathology in medullary thyroid carcinoma

LIU Zhiyan, YU Yaling, KAKUDO Kennichi

Affiliations

LIU Zhiyan, YU Yaling, KAKUDO Kennichi: 1. Department of Pathology, Shanghai Sixth People’s Hospital, Shanghai Jiao Tong University School of Medicine, Shanghai 200233, China;2. Department of Pathology and Thyroid Disease Center, Izumi City General Hospital, Izumi Osaka 594-0073, Japan

DOI: https://doi.org/10.16139/j.1007-9610.2023.06.03
Journal volume & issue: Vol. 28, no. 06
pp. 501 – 506

Abstract

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Medullary thyroid carcinoma (MTC) is a rare thyroid malignancy, which is more aggressive with high metastasis and recurrence rate. Surgical treatment is the preferred treatment option for MTC. Targeted therapy and immunotherapy have gradually become new treatment strategy for MTC. The pathology of MTC was updated in the 5th edition WHO classification of endocrine and neuroendocrine tumor in 2022. This review summarized the update of MTC pathology focusing on the histologic grading schemes, gene screening and genetic counseling.

|medullary thyroid carcinoma|histologic grading scheme|genetic screening|genetic counseling

Published in Waike lilun yu shijian

ISSN: 1007-9610 (Print)
Publisher: Editorial Office of Journal of Surgery Concepts & Practice
Country of publisher: China
LCC subjects: Medicine: Internal medicine: Neoplasms. Tumors. Oncology. Including cancer and carcinogens; Medicine: Surgery
Website: https://www.qk.sjtu.edu.cn/jscp/EN/1007-9610/home.shtml

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