Protocol for the fabrication and application of a low-water-content polyelectrolyte hydrogel

Abstract

Summary: Hydrogels are prone to dehydration over prolonged use, leading to changes in their properties. Inspired by the human skin’s stratum corneum, we present a protocol for the fabrication and application of a low-water-content polyelectrolyte hydrogel (L-hydrogel) that maintains mechanical and electrical properties over time. We describe steps for preparing a hygroscopic monomer through an ionic exchange reaction and a low-water-content hydrogel by UV crosslinking reaction and testing the material behaviors of L-hydrogel. We then detail procedures for preparing and testing L-hydrogel-based devices.For complete details on the use and execution of this protocol, please refer to Shen et al.1 : Publisher’s note: Undertaking any experimental protocol requires adherence to local institutional guidelines for laboratory safety and ethics.

Keywords

• health sciences
• physics
• chemistry
• material sciences