CHARACTERISTICS OF PATIENTS STAYING IN A SPECIALIZED UNIT FOR TUBERCULOSIS PATIENTS WITH CONCURRENT HIV INFECTION

Abstract

The objective of the study: to analyze clinical data of patients staying in a specialized unit for tuberculosis patients with concurrent HIV infection.Subjects and methods. The case histories of all patients staying in the unit for TB/HIV co-infection of Surgut Clinical TB Dispensary discharged in 2016 were retrospectively analyzed, totally there were 231 such patients.Results. Tuberculous lesions in the HIV infected patients were more disseminated (pulmonary disseminated tuberculosis was in 51.1% of patients and generalized forms with lesions in the lungs and other organs were in 17.9% of patients additionally). Cavities were diagnosed in 45.5% of pulmonary tuberculosis patients, and bacillary excretion was detected in 60.4% (among HIVnegative patients, registered in the city, those rates made 38.3 and 42.3% respectively). The rate of multiple drug resistance made 9.9% in all pulmonary tuberculosis patients or 44% among the patients with drug resistance, and extensive drug resistance made 1.4 and 6.1% respectively.Along with anti-tuberculosis chemotherapy, 45.9% of patients received antiretroviral therapy, and 10.0% of them rejected it.Only 36.7% of patients completed the intensive phase of treatment, 29.7% defaulted from treatment and left hospital at their will, 17.5% died, and the remaining patients were transferred to some other medical units (for surgery or to manage some concurrent condition) or they were discharged from the hospital due to violations of the discipline.While on treatment, 57.5% of the patients with bacillary excretion had their sputum converted (by culture).

Keywords

• туберкулез
• вич
• коморбидные инфекции