Nature Communications (Jan 2022)

A genome-wide association study of serum proteins reveals shared loci with common diseases

  • Alexander Gudjonsson,
  • Valborg Gudmundsdottir,
  • Gisli T. Axelsson,
  • Elias F. Gudmundsson,
  • Brynjolfur G. Jonsson,
  • Lenore J. Launer,
  • John R. Lamb,
  • Lori L. Jennings,
  • Thor Aspelund,
  • Valur Emilsson,
  • Vilmundur Gudnason

DOI
https://doi.org/10.1038/s41467-021-27850-z
Journal volume & issue
Vol. 13, no. 1
pp. 1 – 13

Abstract

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Circulating proteins have been linked to many conditions, and understanding their genetic control can lead to understanding of disease. Here, the authors associate common genetic variants with protein levels, finding overlap of genetic associations with circulating proteins and complex disease.