Granular Cell Tumour of Breast-An Enigmatic Entity-Case Report with Emphasis on Role of Frozen Section

Abstract

Granular Cell Tumour (GCT) is a rare tumour involving the breast, pre- and intraoperative diagnosis of which plays an important role in deciding the treatment. Recognition of this usually benign tumour is important, since clinical (irregular and firm), radiological (ill defined or spiculated lesion without microcalcifications) and gross findings often mimic carcinoma. We report a case of a GCT of the breast mimicking carcinoma clinically and on mammography. The diagnosis was made by frozen section, confirmed by histological examination and immunohistochemistry (IHC). We emphasise the role of frozen section and intraoperative diagnosis in guiding treatment and preventing radical surgery. The clinico-radiological, histopathological and therapeutic aspects of this rare tumour, are also discussed.

Keywords

• lump
• mammography
• ultrasonography