Indian Journal of Ophthalmology (Jan 2014)
Outcomes of trabeculectomy in juvenile open angle glaucoma
- Daizy Pathania,
- Sirisha Senthil,
- Harsha L Rao,
- Anil K Mandal,
- Chandra Sekhar Garudadari
Affiliations
- Daizy Pathania
- Sirisha Senthil
- Harsha L Rao
- Anil K Mandal
- Chandra Sekhar Garudadari
- DOI
- https://doi.org/10.4103/0301-4738.101074
- Journal volume & issue
-
Vol. 62,
no. 2
pp. 224 – 228
Abstract
Purpose: This study was aimed at reporting the outcomes of trabeculectomy in primary juvenile open angle glaucoma (JOAG). Design: This study was a retrospective noncomparative case series. Materials and Methods: We included 60 eyes of 41 JOAG patients who underwent primary trabeculectomy without mitomycin-C (MMC) between 1995 and 2007. The primary outcome was success, defined as complete, if intraocular pressure (IOP) was >5 and ≤21 mmHg without medications or qualified if IOP was >5 and ≤21 mmHg with or without antiglaucoma medications. Secondary outcome measures were mean and percentage IOP reduction, complications, and risk factors for the failure of trabeculectomy. Results: The mean (±standard deviation) age at presentation was 24.1 ± 6.8 years (range, 12-35). Mean follow-up was 67 ± 41 months (range, 12-156). At 1 year, the probability of complete success was 92% (n = 56, 95% CI: 81-96%), at 3 years it was 89% (n = 47, 95% CI: 78-95%), and at the end of 5 years, it was 80% (n = 34, 95% CI: 65-89%). The probability of qualified success was 100% (n = 60) at 1 year, 98% (n = 51, 95% CI: 87-100%) at 3 years, and 96% (n = 36, 95% CI: 84-99%) at the end of 5 years. The mean IOP reduced from 35 ± 10 to 13 ± 2.5 mmHg (P < 0.001) after trabeculectomy. There was no serious postoperative complication. Young age was the only significant risk factor associated with the failure (odds ratio = 0.89, P = 0.03). Conclusion: Primary trabeculectomy without MMC has good success rates in JOAG.
Keywords
- Blindness
- cataract
- eye lens
- risk factors
- treatment of cataract
- Low vision care
- multiple disabilities and visual impairment
- reading performance
- Accommodation
- presbyopia
- supraciliary segment implants
- Amblyopia
- citicoline
- patching
- Corneal endothelium
- human corneal endothelial precursor cells
- in vitro expansion
- sphere forming assay
- thermo-reversible gelation polymer
- transportation
- Endophthalmitis
- explantation
- fungal
- intraocular lens
- postoperative
- recurrent
- Colour perception
- learning disabilities
- school children
- stereo acuity
- testability
- visual acuity
- Contracted socket
- dermis fat graft
- porous orbital implant
- reconstruction
- Glucose
- in vitro anticataract
- lens
- Moringa oliefera
- ′BARC I-125 Ocu-Prosta seeds′
- choroidal melanoma
- ciliary body melanoma
- Episcleral plaque brachytherapy
- retinal angioma
- retinoblastoma
- vasoproliferative tumor
- Congenital glaucoma
- gonioscopy
- Retcam
- Acoustic features
- A-scan
- B-scan
- choroidal mass
- ultrasound biomicroscopy
- Cataract surgery
- education
- informed consent
- multimedia
- rural health
- Lagophthalmos
- silicone sling
- temporalis muscle
- Contrast sensitivity function
- disability
- function peak
- multiple sclerosis
- spatial frequency
- Congenital cataract
- developmental cataract
- outcome
- vision function
- Bacterial
- extracellular enzymes
- fungal
- keratitis
- toxins
- Exotropic Duane retraction syndrome
- periosteal fixation
- strabismus surgery
- vertical rectus transposition
- Descemet′s stripping endothelial keratoplasty
- complications
- donor dislocation
- endothelial cell loss
- graft failure
- management
- Glaucoma
- glaucoma experimental
- parapapillary atrophy
- Juvenile open angle glaucoma
- juvenile glaucoma
- primary trabeculectomy
- trabeculectomy in young