An efficient synthesis of N-substituted pyrroles catalyzed by MgI2 etherate

Zhang Yongdong; Weng Guodong; Chen Jingyan; Ma Danting; Zhang Xingxian

doi:10.1515/mgmc-2014-0031

Main Group Metal Chemistry (Dec 2014)

An efficient synthesis of N-substituted pyrroles catalyzed by MgI2 etherate

Zhang Yongdong,
Weng Guodong,
Chen Jingyan,
Ma Danting,
Zhang Xingxian

Affiliations

Zhang Yongdong: College of Pharmaceutical Sciences, Zhejiang University of Technology, Hangzhou, Zhejiang 310014, People’s Republic of China
Weng Guodong: College of Pharmaceutical Sciences, Zhejiang University of Technology, Hangzhou, Zhejiang 310014, People’s Republic of China
Chen Jingyan: College of Pharmaceutical Sciences, Zhejiang University of Technology, Hangzhou, Zhejiang 310014, People’s Republic of China
Ma Danting: College of Pharmaceutical Sciences, Zhejiang University of Technology, Hangzhou, Zhejiang 310014, People’s Republic of China
Zhang Xingxian: College of Pharmaceutical Sciences, Zhejiang University of Technology, Hangzhou, Zhejiang 310014, People’s Republic of China

DOI: https://doi.org/10.1515/mgmc-2014-0031
Journal volume & issue: Vol. 37, no. 5-6
pp. 131 – 135

Abstract

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We describe a convenient and useful procedure for the synthesis of various 2,5-dimethyl-N-substituted pyrrole derivatives by the addition of 2,5-hexadione with aromatic amines, heteroaromatic amines and aliphatic amines catalyzed by MgI2 etherate (MgI2·(OEt2)n) in good to excellent yields.

Published in Main Group Metal Chemistry

ISSN: 0792-1241 (Print); 2191-0219 (Online)
Publisher: De Gruyter
Country of publisher: Poland
LCC subjects: Science: Chemistry
Website: https://www.degruyter.com/view/j/mgmc

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