Emerging Infectious Diseases (Nov 2011)

Ultrastructural Characterization of Pandemic (H1N1) 2009 Virus

  • Cynthia S. Goldsmith,
  • Maureen G. Metcalfe,
  • Dominique C. Rollin,
  • Wun-Ju Shieh,
  • Christopher D. Paddock,
  • Xiyan Xu,
  • Sherif R. Zaki

DOI
https://doi.org/10.3201/eid1711.110258
Journal volume & issue
Vol. 17, no. 11
pp. 2056 – 2059

Abstract

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We evaluated pandemic influenza A (H1N1) 2009 virus isolates and respiratory tissues collected at autopsy by electron microscopy. Many morphologic characteristics were similar to those previously described for influenza virus. One of the distinctive features was dense tubular structures in the nuclei of infected cells.

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