Current therapeutic approaches to locally advanced rectal cancer

Abstract

Surgery remains the main treatment for non-metastatic colorectal cancer. These patients undergo radical operation (when possible) or cytoreductive surgery with the excision of most tumor tissue. Neoadjuvant radiotherapy is also an important step of treatment in patients with lower and middle rectal tumors. However, randomized clinical trials indicate that combination neoadjuvant treatment that includes polychemotherapy and radiotherapy is more effective.

Keywords

• rectal cancer
• radiotherapy
• chemotherapy
• combination treatment