Nature Communications (Mar 2023)
Lateral hypothalamic leptin receptor neurons drive hunger-gated food-seeking and consummatory behaviours in male mice
- Young Hee Lee,
- Yu-Been Kim,
- Kyu Sik Kim,
- Mirae Jang,
- Ha Young Song,
- Sang-Ho Jung,
- Dong-Soo Ha,
- Joon Seok Park,
- Jaegeon Lee,
- Kyung Min Kim,
- Deok-Hyeon Cheon,
- Inhyeok Baek,
- Min-Gi Shin,
- Eun Jeong Lee,
- Sang Jeong Kim,
- Hyung Jin Choi
Affiliations
- Young Hee Lee
- Department of Biomedical Sciences, Seoul National University College of Medicine
- Yu-Been Kim
- Department of Biomedical Sciences, Seoul National University College of Medicine
- Kyu Sik Kim
- Department of Biomedical Sciences, Seoul National University College of Medicine
- Mirae Jang
- Department of Biomedical Sciences, Seoul National University College of Medicine
- Ha Young Song
- Department of Biomedical Sciences, Seoul National University College of Medicine
- Sang-Ho Jung
- Department of Biomedical Sciences, Seoul National University College of Medicine
- Dong-Soo Ha
- Department of Biomedical Sciences, Seoul National University College of Medicine
- Joon Seok Park
- Department of Biomedical Sciences, Seoul National University College of Medicine
- Jaegeon Lee
- Department of Biomedical Sciences, Seoul National University College of Medicine
- Kyung Min Kim
- Department of Biomedical Sciences, Seoul National University College of Medicine
- Deok-Hyeon Cheon
- Department of Biomedical Sciences, Seoul National University College of Medicine
- Inhyeok Baek
- Department of Biomedical Sciences, Seoul National University College of Medicine
- Min-Gi Shin
- Department of Brain Science, Ajou University School of Medicine
- Eun Jeong Lee
- Department of Brain Science, Ajou University School of Medicine
- Sang Jeong Kim
- Department of Biomedical Sciences, Seoul National University College of Medicine
- Hyung Jin Choi
- Department of Biomedical Sciences, Seoul National University College of Medicine
- DOI
- https://doi.org/10.1038/s41467-023-37044-4
- Journal volume & issue
-
Vol. 14,
no. 1
pp. 1 – 16
Abstract
Eating behviours consist of seeking and consummatory phases. Here, authors show that two distinct lateral hypothalamic leptin receptor neurons orchestrate seeking and consummatory phases of eating behaviour via hunger signal, Neuropeptide Y.
