Nature Communications (Feb 2016)

Microbial metabolomics in open microscale platforms

  • Layla J. Barkal,
  • Ashleigh B. Theberge,
  • Chun-Jun Guo,
  • Joe Spraker,
  • Lucas Rappert,
  • Jean Berthier,
  • Kenneth A. Brakke,
  • Clay C. C. Wang,
  • David J. Beebe,
  • Nancy P. Keller,
  • Erwin Berthier

DOI
https://doi.org/10.1038/ncomms10610
Journal volume & issue
Vol. 7, no. 1
pp. 1 – 11

Abstract

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Traditional methods for microbial culture and subsequent metabolomics are time-consuming and labour-intensive. Here the authors present a microscale culture platform with integrated extraction for efficient, low-volume metabolomics of relevant microenvironments and microbial co-cultures.