Nature Communications (Sep 2022)

An anti-inflammatory activation sequence governs macrophage transcriptional dynamics during tissue injury in zebrafish

  • Nicolas Denans,
  • Nhung T. T. Tran,
  • Madeleine E. Swall,
  • Daniel C. Diaz,
  • Jillian Blanck,
  • Tatjana Piotrowski

DOI
https://doi.org/10.1038/s41467-022-33015-3
Journal volume & issue
Vol. 13, no. 1
pp. 1 – 15

Abstract

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Macrophages are important for tissue regeneration after injury. Here, using a single cell sequencing approach in a zebrafish injury model, the authors show that macrophages transition through a three stage process during tissue regeneration after hair cell damage.