Frontiers in Pediatrics (Oct 2019)
Comparison of Pulmonary Artery Pressure Measurement With Doppler Echocardiography or With Right Heart Catheterization in Patients With Congenital Heart Disease
- Dan Yin,
- Dan Yin,
- Dan Yin,
- Dan Yin,
- Dan Yin,
- Ying Wang,
- Ying Wang,
- Ying Wang,
- Ying Wang,
- Ying Wang,
- Min Zheng,
- Min Zheng,
- Min Zheng,
- Min Zheng,
- Min Zheng,
- Huijing Wei,
- Huijing Wei,
- Huijing Wei,
- Huijing Wei,
- Huijing Wei,
- Mi Li,
- Mi Li,
- Mi Li,
- Mi Li,
- Mi Li,
- Tiewei Lv,
- Tiewei Lv,
- Tiewei Lv,
- Tiewei Lv,
- Tiewei Lv,
- Yonghong Bai,
- Yonghong Bai,
- Yonghong Bai,
- Yonghong Bai,
- Yonghong Bai,
- Jie Tian,
- Jie Tian,
- Jie Tian,
- Jie Tian,
- Jie Tian,
- Xiaoyun Wu,
- Xiaoyun Wu,
- Xiaoyun Wu,
- Xiaoyun Wu,
- Xiaoyun Wu
Affiliations
- Dan Yin
- Ministry of Education Key Laboratory of Child Development and Disorders, Chongqing, China
- Dan Yin
- China International Science and Technology Cooperation Base of Child Development and Critical Disorders, Chongqing, China
- Dan Yin
- Department of Cardiovascular Medicine, Children's Hospital of Chongqing Medical University, Chongqing, China
- Dan Yin
- National Clinical Research Center for Child Health and Disorders, Chongqing, China
- Dan Yin
- Chongqing Key Laboratory of Pediatrics, Chongqing, China
- Ying Wang
- Ministry of Education Key Laboratory of Child Development and Disorders, Chongqing, China
- Ying Wang
- China International Science and Technology Cooperation Base of Child Development and Critical Disorders, Chongqing, China
- Ying Wang
- Department of Cardiovascular Medicine, Children's Hospital of Chongqing Medical University, Chongqing, China
- Ying Wang
- National Clinical Research Center for Child Health and Disorders, Chongqing, China
- Ying Wang
- Chongqing Key Laboratory of Pediatrics, Chongqing, China
- Min Zheng
- Ministry of Education Key Laboratory of Child Development and Disorders, Chongqing, China
- Min Zheng
- China International Science and Technology Cooperation Base of Child Development and Critical Disorders, Chongqing, China
- Min Zheng
- Department of Cardiovascular Medicine, Children's Hospital of Chongqing Medical University, Chongqing, China
- Min Zheng
- National Clinical Research Center for Child Health and Disorders, Chongqing, China
- Min Zheng
- Chongqing Key Laboratory of Pediatrics, Chongqing, China
- Huijing Wei
- Ministry of Education Key Laboratory of Child Development and Disorders, Chongqing, China
- Huijing Wei
- China International Science and Technology Cooperation Base of Child Development and Critical Disorders, Chongqing, China
- Huijing Wei
- Department of Cardiovascular Medicine, Children's Hospital of Chongqing Medical University, Chongqing, China
- Huijing Wei
- National Clinical Research Center for Child Health and Disorders, Chongqing, China
- Huijing Wei
- Chongqing Key Laboratory of Pediatrics, Chongqing, China
- Mi Li
- Ministry of Education Key Laboratory of Child Development and Disorders, Chongqing, China
- Mi Li
- China International Science and Technology Cooperation Base of Child Development and Critical Disorders, Chongqing, China
- Mi Li
- Department of Cardiovascular Medicine, Children's Hospital of Chongqing Medical University, Chongqing, China
- Mi Li
- National Clinical Research Center for Child Health and Disorders, Chongqing, China
- Mi Li
- Chongqing Key Laboratory of Pediatrics, Chongqing, China
- Tiewei Lv
- Ministry of Education Key Laboratory of Child Development and Disorders, Chongqing, China
- Tiewei Lv
- China International Science and Technology Cooperation Base of Child Development and Critical Disorders, Chongqing, China
- Tiewei Lv
- Department of Cardiovascular Medicine, Children's Hospital of Chongqing Medical University, Chongqing, China
- Tiewei Lv
- National Clinical Research Center for Child Health and Disorders, Chongqing, China
- Tiewei Lv
- Chongqing Key Laboratory of Pediatrics, Chongqing, China
- Yonghong Bai
- Ministry of Education Key Laboratory of Child Development and Disorders, Chongqing, China
- Yonghong Bai
- China International Science and Technology Cooperation Base of Child Development and Critical Disorders, Chongqing, China
- Yonghong Bai
- Department of Cardiovascular Medicine, Children's Hospital of Chongqing Medical University, Chongqing, China
- Yonghong Bai
- National Clinical Research Center for Child Health and Disorders, Chongqing, China
- Yonghong Bai
- Chongqing Key Laboratory of Pediatrics, Chongqing, China
- Jie Tian
- Ministry of Education Key Laboratory of Child Development and Disorders, Chongqing, China
- Jie Tian
- China International Science and Technology Cooperation Base of Child Development and Critical Disorders, Chongqing, China
- Jie Tian
- Department of Cardiovascular Medicine, Children's Hospital of Chongqing Medical University, Chongqing, China
- Jie Tian
- National Clinical Research Center for Child Health and Disorders, Chongqing, China
- Jie Tian
- Chongqing Key Laboratory of Pediatrics, Chongqing, China
- Xiaoyun Wu
- Ministry of Education Key Laboratory of Child Development and Disorders, Chongqing, China
- Xiaoyun Wu
- China International Science and Technology Cooperation Base of Child Development and Critical Disorders, Chongqing, China
- Xiaoyun Wu
- Department of Cardiovascular Medicine, Children's Hospital of Chongqing Medical University, Chongqing, China
- Xiaoyun Wu
- National Clinical Research Center for Child Health and Disorders, Chongqing, China
- Xiaoyun Wu
- Chongqing Key Laboratory of Pediatrics, Chongqing, China
- DOI
- https://doi.org/10.3389/fped.2019.00421
- Journal volume & issue
-
Vol. 7
Abstract
Background: Doppler echocardiography (D-ECHO) is a commonly used imaging tool for both diagnosis and follow-up examination of congenital heart disease (CHD). The goal of this study is to evaluate the accuracy of D-ECHO as used to measure an estimate sPAP in pediatric patients with CHD.Methods: A prospective study in 397 pediatric patients with CHD has been carried out to compare estimate sPAP measured with D-ECHO to that measured with right heart catheterization (RHC). Pearson correlation analyses were used to calculate the correlation coefficients between RHC and D-ECHO. Bland-Altman analyses were carried out to assess the agreement between the two methods.Results: Our data have demonstrated a significant underestimation of sPAP by D-ECHO compared to that by RHC. A strong correlation (r = 0.957, p < 0.01) was found between sPAP (36.1 ± 14.9 mmHg) and RVSP (36.0 ± 14.5 mmHg) measured with RHC. However, a relatively weak correlation (r = 0.219, p < 0.01) was observed between sPAP (36.1 ± 14.9 mmHg) measured during RHC and sPAP (28.7 ± 9.7 mmHg) as estimated using D-ECHO. The Bland-Altman analysis demonstrated that the bias for D-ECHO sPAP estimates was 6.6 mmHg with 95% limits of agreement ranging from −23.6 to 36.8 mmHg. A total of 57.5% of D-ECHO measurements were found to be accurate, with accuracy predefined as 95% of agreement within ±10 mmHg for sPAP estimates.Conclusions: sPAP measured with D-ECHO may be underestimated in pediatric patients with CHD.
Keywords
- pediatrics
- congenital heart disease
- echocardiography
- systolic pulmonary artery pressure
- right heart catheterization
